Dr. Johnathan Wright Discusses The Benefits of Berberine For Diabetes
So, Dr. Jonathan Wright, you were talking about berberine, and you were comparing it to metformin which is a medication for diabetes. Right. Really impressive results, reducing cholesterol, triglycerides, glucose after 90 days. Oh, well remember one thing. These aren't my studies. These are studies published in journals called Metabolism and Journal of Endocrinology and Metabolism. What those researchers showed is that the berberine could reduce the blood sugar not just in 90 days, but the majority of the beneficial effect was within the first ten days, and the blood sugars would come down significantly in that time. Now they did extend their studies to 90 days to see how much further they could get, and they did get a little further.
It lowered the blood sugar, it lowered the hemoglobin A of course right along with it, but oddly enough, it raised the good cholesterol and it lowered the bad cholesterol. The LDL, yeah. Yeah, and all around, it's one of the better things one can do if you have Type 2 diabetes or if you don't want to get Type 2 diabetes and you think you're on the way because your doctor has done the appropriate tests to find out. And little or no side effects. If they had a little GI effect, you just reduced from 500 milligrams three times a day, to 300 milligrams three times a day.
Well, the important part is most of the side effects came when the [popup_product]berberine[/popup_product] was taken with a patent medication or some other treatment. When they were separated, there were no side effects. Beautiful, beautiful. You also cleared up something for me and that was that I've read on the Internet and elsewhere that berberine isn't something you would continually take, and you made an eloquent statement regarding the microflora and the bacteria. Tell us about that. Well, it was actually elegant research. What the research did was to examine the entire bacterial flora. How do you do that? By DNA studies. They did DNA of each of the little bacteria in the gut, and this is in experimental animals now. So they ID'd, here are all these different bacteria in a number of animals and then they had fed them berberine or they had feed themselves berberine I forget which, and after X amount of months, they then went and did the DNA analysis of the microbiome after berberine, and they found out that, sure enough, while a certain number of bacteria simply disappeared, those were all the bacteria we don't want to have anyway.
The bad ones. And the good ones almost entirely survived. There are other herbs that are known to do that though. We know, for example, that oregano has much the same effect. It will clean up bad bacteria and not touch the good guy bacteria. So that is not a unique thing, it's just nice to know that berberine is in the group that cleans up the bad ones and doesn't much mess with the good ones. So the net result is diabetics tend to have the highest incidence of gangrenous limbs, they get amputated, they have a high rate of stroke, they have a high rate of cardiovascular complications, they have ED.
Some people feel that it's not just the blood sugar and the insulin metabolism problems but their elevated LDL, their elevated triglycerides. What you showed with the berberine — Remember it was the researchers that showed it. Yes, yes, which you showed, well, you presented based on the research, was that there was an improvement, a significant improvement in the lipid profiles, the glucose. The triglycerides came down, the HDL went up, the LDL went down, yeah, very nice.
Everyone, I mean, it has become epidemic proportion, people all over the world, not just our country, is suffering from diabetes. Well of course though, the berberine is step number 3. We have to do the diet right first and the exercise second and then we bring in the supplements, but berberine is indeed the number one supplement. Share with us, while we're talking about the herbal interventions of phytochemical; turmeric, curcumin, some people say, well it doesn't absorb very well.
Can you just use a fatty acid component, something that would help to improve or does it just overall, absorb pretty well as it is? No, it doesn't. So it does need some — There are the more absorbable curcumin fractions. Now I'm not aware that that has an enormous impact on diabetes as berberine does on Type 2. We've got to be clear of Type 2. But there are a number of other botanicals that also work against diabetes, it's just berberine has assumed number one place just because it does so well.
What else have you found in the literature? My goodness, there is, what is it, it's some cucumber — bittermelon, that's it. Bitter melon is helpful. Other stuff in there called Gymnema. It's an ayurvedic herb. There are several more. Those I tend to keep not on a file card anymore but in the right place on the computer so I can find them all, but there are several botanicals.
Beautiful, beautiful. Clearly, diabetics are going to benefit from exercise, from a healthy diet, from better sleep. Remember there's even research on what kind of exercise does best. Intense? The intense exercise, this so-called interval training or putting yourself into anaerobic metabolism briefly. You don't want to do it for too long. You'll get lactic acid too much in your muscles. Except for those people with a genetic deficiency of lactic acid. Who can't make lactic acid, that's true. So the benefit of the exercise has been — let me put it another way. Restart over again here, reset. That is with the intense interval training type exercise, it does much better than jogging than moderate aerobic exercise. I'm glad you say that because that's something I'm a big proponent of. I enjoy it myself. I experience the benefits. So a person who starts but doesn't want to start out really intense. It's a little hard to their body to adjust. You work into it. You build up. Yeah, very good. So in working through with the combination of, do you think it's appropriate to take phytochemical herbs and supplements and work them together with biomedical hormones where it's necessary? There's a point where some people need some hormonal support as well too.
Well, it's not only appropriate, it's a damn good idea because we're trying to look at the health of the whole body, not just the blood sugar regulation system which is an important one but still, it's the whole body. The only thing we have to be really careful about is the testosterone. Just about all the hormones help to improve the blood sugar. Testosterone can too, but darn it, when we have the Type 2 diabetes that if we still have the high insulin signal, it can make too much testosterone turning into estrogen and that's very counterproductive for guys.
So we have to be much more careful about the use of testosterone. I'm not saying don't use it. I'm saying we have to do all the monitoring to make sure we're not hyperaromatasing. We have to get that, not blocked with the patent medicine, but we have to get that slowed down by natural means…